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DataTítuloAutor(es)TipoAcesso
2004A IMUNOESTIMULAÇÃO DA BILIRRUBINA É AGRAVADA PELA SEPSIS, ENVOLVE A ACTIVAÇÃO DO NF-KB E DO ARNM DA IL-1BETA E DO TNF-ALFA E É DIVERSAMENTE MODULADA PELA IL-10 E PELO GLICO-URSODESOXICOLATOFernandes, A; Falcão, AS; Gordo, AC; Gama, MJ; Silva, RFM; Brito, MA; Brites, DarticlerestrictedAccess
2003Ability of glycoursodeoxycholate to prevent astrocyte injury by bilirubin may be restricted to the membrane pathway-dependent cytotoxicityFernandes, A; Falcao, AS; Silva, RF; Brito, MA; Brites, DarticlerestrictedAccess
2003Are interleukins new players in the pathophysiology of bilirubin encephalopathy?Falcao, AS; Fernandes, A; Brito, MA; Silva, RF; Brites, DarticlerestrictedAccess
2004ASTROGLIAL RESPONSE TO BILIRUBIN INVOLVES THE ACTIVATION OF THE TNF-ALPHA AND NF-KAPPAB PATHWAYSFernandes, A; Falcão, AS; Gordo, C; Gama, MJ; Silva, RFM; Brito, MA; Brites, DarticlerestrictedAccess
2006Bilirubin-induced immunostimulant effects and toxicity vary with neural cell type and maturation stateFalcao, AS; Fernandes, A; Brito, MA; Silva, RFM; Brites, DarticlerestrictedAccess
2005Bilirubin-induced inflammatory response, glutamate release, and cell death in rat cortical astrocytes are enhanced in younger cellsFalcao, AS; Fernandes, A; Brito, MA; Silva, RFM; Brites, DarticlerestrictedAccess
2004Bilirubin-induced release of cytokines and glutamate depends from neural cell type and decreases with differentiationFalcao, AS; Fernandes, A; Brito, MA; Silva, RF; Brites, DarticlerestrictedAccess
2002Bilirubin-induced TNF-alpha release and apoptosis in astrocytes is enhanced by endotoxin, even at clinically relevant concentrations.Silva, RF; Brito, MA; Fernandes, A; Correia, LE; Brites, DarticlerestrictedAccess
2004Cytokine production, glutamate release and cell death in rat cultured astrocytes treated with unconjugated bilirubin and LPSFernandes, A; Silva, RFM; Falcao, AS; Brito, MA; Brites, DarticlerestrictedAccess
2005DISSECTING ASTROCYTE REACTIVITY BY UNCONJUGATED BILIRUBINFernandes, A; Falcão, AS; Gordo, C; Gama, MJ; Silva, RFM; Brito, MA; Brites, DarticlerestrictedAccess
2006Dissociated primary nerve cell cultures as models for assessment of neurotoxicitySilva, RFM; Falcao, AS; Fernandes, A; Gordo, AC; Brito, MA; Brites, DarticlerestrictedAccess
2005Hyperbilirubinemia induces oxidative stress in rat brain primary neuronal culturesBrito, MA; Rosa, AI; Fernandes, A; Falcao, AS; Silva, RFM; Brites, DarticlerestrictedAccess
2005Increased apoptosis and decreased p53 and Bax expression in colorectal tumoursBorralho, PM; Ravasco, P; da Silva, IBM; Castro, RE; Ramalho, RM; Sola, S; Correia, L; Fernandes, A; Camilo, ME; Rodrigues, CMParticlerestrictedAccess
2006Inflammatory signalling pathways involved in astroglial activation by unconjugated bilirubinFernandes, A; Falcao, AS; Silva, RFM; Gordo, AC; Gama, MJ; Brito, MA; Brites, DarticlerestrictedAccess
2001Influence of the interval between the administration of doxorubicin and paclitaxel on the pharmacokinetics of these drugs in patients with locally advanced breast cancerMoreira, A; Lobato, R; Morais, J; Silva, S; Ribeiro, J; Figueira, A; Vale, D; Sousa, C; Araujo, F; Fernandes, A; Oliveira, J; Passos-Coelho, JLarticlerestrictedAccess
2003Interleukin-10 modulates the immune stimulant effect of bilirubin in ratastroglial cellsFernandes, A; Falcao, AS; Silva, RFM; Brito, MA; Brites, DarticlerestrictedAccess
2008Methylmethacrylate monomer in acrylic bone cement toxicityBettencourt, A; Fernandes, A; Oliveira, N; Monteiro, J; Calado, A; Castro, MarticlerestrictedAccess
2009Microglia acquires a phagocytic or pro-inflammatory phenotype when bilirubin gets into the brainLeitão Silva S, Osório C,; Barateiro, A; Falcão, AS; Brito, MA; Fernandes, A; Silva, RFM; Brites, DarticlerestrictedAccess
2007Oxidative stress and disruption of the nervous cellBrito, MA; Rosa, AI; Silva, RFM; Falcão, AS; Fernandes, A; Brites, DarticlerestrictedAccess
2005Putative role of a decreased MRP1 expression in immature astrocytes in the susceptibility to biurubin-induced toxicityFalcao, AS; Bellarosa, C; Fernandes, A; Brito, MA; Silva, RFM; Tiribelli, C; Brites, DarticlerestrictedAccess