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20055-Fluorouracil differentially modulates apoptosis of colorectal cancer cellsda Silva, IBM; Borralho, PM; Castro, RE; Ramalho, RM; Albuquerque, C; Laitao, CN; Rodrigues, CMParticlerestrictedAccess
2001A bile acid protects against motor and cognitive deficits and reduces striatal degeneration in the 3-nitropropionic acid model of Huntington's diseaseKeene, CD; Rodrigues, CMP; Eich, T; Linehan-Stieers, C; Abt, A; Kren, BT; Steer, CJ; Low, WCarticlerestrictedAccess
2005A distinct microarray gene expression profile in primary rat hepatocytes incubated with ursodeoxycholic acidCastro, RE; Sola, S; Ma, XM; Ramalho, RM; Kren, BT; Steer, CJ; Rodrigues, CMParticlerestrictedAccess
2002Aging confers different sensitivity to the neurotoxic properties of unconjugated bilirubinRodrigues, CMP; Sola, S; Silva, RFM; Brites, DarticlerestrictedAccess
2001Amyloid beta-peptide disrupts mitochondrial membrane lipid and protein structureRodrigues, CMP; Sola, S; Brito, MA; Brondino, CD; Brites, D; Moura, JJGarticlerestrictedAccess
2000Apoptosis induced by deoxycholic acid unconjugated bilirubin and amyloid beta-peptide reflects mitochondrial perturbation which may be inhibited by ursodeoxycholic acidRodrigues, CMP; Sola, S; Silva, R; Diogenes, MJ; Brites, DarticlerestrictedAccess
2000Apoptotic cell death does not parallel other indicators of liver damage in chronic hepatitis C patientsRodrigues, CMP; Brites, D; Serejo, F; Costa, A; Ramalho, F; de Moura, MCarticlerestrictedAccess
2003Association between hepatocellular apoptosis and inflammation in patients with non-alcoholic and alcoholic steatohepatitisRibeiro, PS; Cortez-Pinto, H; Sola, S; Castro, RE; Baptista, A; Camilo, ME; Moura, MC; Rodrigues, CMParticlerestrictedAccess
2001Bilirubin activates caspase-3-dependent apoptotic signaling cascadeRodrigues, CMP; Sola, S; Brito, MA; Moura, JG; Brites, DarticlerestrictedAccess
2000Bilirubin and amyloid-beta peptide induce cytochrome c release through mitochondrial membrane permeabilizationRodrigues, CMP; Sola, S; Silva, R; Brites, DarticlerestrictedAccess
2002Bilirubin directly disrupts membrane lipid polarity and fluidity, protein order. and redox status in rat mitochondriaRodrigues, CMP; Sola, S; Brito, MA; Brites, D; Moura, JJGarticlerestrictedAccess
2002Bilirubin induces apoptosis via the mitochondrial pathway in developing rat brain neuronsRodrigues, CMP; Sola, S; Brites, DarticlerestrictedAccess
2001Bilirubin-induced apoptosis in cultured rat neural cells is aggravated by chenodeoxycholic acid but prevented by ursodeoxycholic acidsSilva, RFM; Rodrigues, CMP; Brites, DarticlerestrictedAccess
2001Creatine-supplemented diet extends purkinje cell survival in spinocerebellar ataxia type 1 transgenic mice but does not prevent the ataxic phenotypeKaemmerer, WF; Rodrigues, CMP; Steer, CJ; Low, WCarticlerestrictedAccess
2002Differential expression of Bcl-2 gene family induced by transforming growth factor beta1 (TGF-beta1) is regulated by ursodeoxycholate (UDC)Sola, S; Laires, PA; Castro, RE; Ma, XM; Kren, BT; Steer, CJ; Rodrigues, CMParticlerestrictedAccess
2004Enhanced apoptosis and Bcl-2 protein production in the liver of patients with steatohepatitisRamalho, RM; Cortez-Pinto, H; Sola, S; Castro, RE; Camilo, ME; Moura, MC; Rodrigues, CMParticlerestrictedAccess
2008Evaluation of the protective role of glutathione S-transferase pi against MPTP neurotoxicityGama, MJ; Carvalho, ANeves; Rodrigues, E; Castro-Caldas, M; Rodrigues, CMParticlerestrictedAccess
2004Hepatocyte apoptosis, expression of death receptors, and activation of NF-kappa B in the liver of nonalcoholic and alcoholic steatohepatitis patientsRibeiro, PS; Cortez-Pinto, H; Sola, S; Castro, RE; Ramalho, RM; Baptista, A; Moura, MC; Camilo, ME; Rodrigues, CMParticlerestrictedAccess
2005Increased apoptosis and decreased p53 and Bax expression in colorectal tumoursBorralho, PM; Ravasco, P; da Silva, IBM; Castro, RE; Ramalho, RM; Sola, S; Correia, L; Fernandes, A; Camilo, ME; Rodrigues, CMParticlerestrictedAccess
2004Inhibition of the E2F-1/p53/Bax pathway by tauroursodeoxycholic acid in amyloid beta-peptide-induced apoptosis of PC12 CellsRamalho, RM; Ribeiro, PS; Sola, S; Castro, RE; Steer, CJ; Rodrigues, CMParticlerestrictedAccess