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DataTítuloAutor(es)TipoAcesso
2004A IMUNOESTIMULAÇÃO DA BILIRRUBINA É AGRAVADA PELA SEPSIS, ENVOLVE A ACTIVAÇÃO DO NF-KB E DO ARNM DA IL-1BETA E DO TNF-ALFA E É DIVERSAMENTE MODULADA PELA IL-10 E PELO GLICO-URSODESOXICOLATOFernandes, A; Falcão, AS; Gordo, AC; Gama, MJ; Silva, RFM; Brito, MA; Brites, DarticlerestrictedAccess
2002Aging confers different sensitivity to the neurotoxic properties of unconjugated bilirubinRodrigues, CMP; Sola, S; Silva, RFM; Brites, DarticlerestrictedAccess
2004ASTROGLIAL RESPONSE TO BILIRUBIN INVOLVES THE ACTIVATION OF THE TNF-ALPHA AND NF-KAPPAB PATHWAYSFernandes, A; Falcão, AS; Gordo, C; Gama, MJ; Silva, RFM; Brito, MA; Brites, DarticlerestrictedAccess
2002Bilirubin induces loss of membrane lipids and exposure of phosphatidylserine in human erythrocytesBrito, MA; Silva, RFM; Brites, DarticlerestrictedAccess
2001Bilirubin-induced apoptosis in cultured rat neural cells is aggravated by chenodeoxycholic acid but prevented by ursodeoxycholic acidsSilva, RFM; Rodrigues, CMP; Brites, DarticlerestrictedAccess
2006Bilirubin-induced immunostimulant effects and toxicity vary with neural cell type and maturation stateFalcao, AS; Fernandes, A; Brito, MA; Silva, RFM; Brites, DarticlerestrictedAccess
2005Bilirubin-induced inflammatory response, glutamate release, and cell death in rat cortical astrocytes are enhanced in younger cellsFalcao, AS; Fernandes, A; Brito, MA; Silva, RFM; Brites, DarticlerestrictedAccess
2006Cell response to hyperbilirubinemiaBrito, MA; Silva, RFM; Brites, DarticlerestrictedAccess
2001Comparative study of adverse effects of hyperbilirubinaemia on foetal and adult erythrocytes. Influence of acidosisBrites, D; Brito, MA; Matos, D; Silva, RFMarticlerestrictedAccess
2004Cytokine production, glutamate release and cell death in rat cultured astrocytes treated with unconjugated bilirubin and LPSFernandes, A; Silva, RFM; Falcao, AS; Brito, MA; Brites, DarticlerestrictedAccess
2005DISSECTING ASTROCYTE REACTIVITY BY UNCONJUGATED BILIRUBINFernandes, A; Falcão, AS; Gordo, C; Gama, MJ; Silva, RFM; Brito, MA; Brites, DarticlerestrictedAccess
2006Dissociated primary nerve cell cultures as models for assessment of neurotoxicitySilva, RFM; Falcao, AS; Fernandes, A; Gordo, AC; Brito, MA; Brites, DarticlerestrictedAccess
2001Endocytosis in rat cultured astrocytes is inhibited by unconjugated bilirubinSilva, RFM; Mata, LM; Gulbenkian, S; Brites, DarticlerestrictedAccess
2006Functional significance of SP1 and SP3 transcription factors in the regulation of the human CYP46A1 promoter - cross-talk with CCAAT/enhancer binding proteinsRodrigues, E; Milagre, I; Gama, MJ; Silva, RFM; Falcão, AS; Pascussi, JM; Lechner, MCarticlerestrictedAccess
2005Hyperbilirubinemia induces oxidative stress in rat brain primary neuronal culturesBrito, MA; Rosa, AI; Fernandes, A; Falcao, AS; Silva, RFM; Brites, DarticlerestrictedAccess
2006Inflammatory signalling pathways involved in astroglial activation by unconjugated bilirubinFernandes, A; Falcao, AS; Silva, RFM; Gordo, AC; Gama, MJ; Brito, MA; Brites, DarticlerestrictedAccess
2003Interleukin-10 modulates the immune stimulant effect of bilirubin in ratastroglial cellsFernandes, A; Falcao, AS; Silva, RFM; Brito, MA; Brites, DarticlerestrictedAccess
2009Microglia acquires a phagocytic or pro-inflammatory phenotype when bilirubin gets into the brainLeitão Silva S, Osório C,; Barateiro, A; Falcão, AS; Brito, MA; Fernandes, A; Silva, RFM; Brites, DarticlerestrictedAccess
2007Oxidative stress and disruption of the nervous cellBrito, MA; Rosa, AI; Silva, RFM; Falcão, AS; Fernandes, A; Brites, DarticlerestrictedAccess
2005Putative role of a decreased MRP1 expression in immature astrocytes in the susceptibility to biurubin-induced toxicityFalcao, AS; Bellarosa, C; Fernandes, A; Brito, MA; Silva, RFM; Tiribelli, C; Brites, DarticlerestrictedAccess