Universidade de Lisboa Repositório da Universidade de Lisboa

Repositório da Universidade de Lisboa >
Faculdade de Medicina (FM) >
FM - Teses de Doutoramento >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10451/1132

Título: Anti-parkinsonian drugs and sleep disorders in Parkinson s disease
Autor: Ferreira, Joaquim, 1968-
Orientador: Sampaio, Cristina, 1963-
Rascol, Olivier
Palavras-chave: Doença de Parkinson
Transtornos do sono
Distúrbios do início e da manutenção do sono
Teses de doutoramento
Issue Date: 2009
Resumo: Sleep disturbances are a frequent and relevant clinical phenomenon for the management of Parkinson's disease (PD). It is estimated that 60% to 90% of the patients with PD complain of difficulties associated with sleep and these disorders can be categorized into those that involve nocturnal sleep and daytime manifestations such as excessive daytime sleepiness. The causes of sleep disorders in PD are considered to be multifactorial: related to the disease itself, to co-morbidity or ageing, or even linked to the direct or indirect effects to the numerous drugs prescribed to these patients. All of the hypothesised factors have to be incorporated into the methodology of studies designed to approach this problem. This dissertation presents several research projects conducted to better understand the phenomenology of somnolence and other sleep disorders as adverse effects of antiparkinsonian drugs, and to contribute to their clinical management. The research projects cover different aspects of this topic and intentionally apply different study methodologies, from case reports (observational studies) to systematic reviews, including cross-sectional studies, clinical trials and other study designs.
Descrição: Tese de doutoramento, Medicina (Neurologia), 2009, Universidade de Lisboa, Faculdade de Medicina
URI: http://catalogo.ul.pt/F/?func=item-global&doc_library=ULB01&type=03&doc_number=000559261
Appears in Collections:FM - Teses de Doutoramento

Files in This Item:

File Description SizeFormat
19098_ulsd_re403_Tese_Dout_FML_J_Ferreira_2009.pdf1,18 MBAdobe PDFView/Open
Restrict Access. You can request a copy!

Please give feedback about this item
FacebookTwitterDeliciousLinkedInDiggGoogle BookmarksMySpace
Formato BibTex MendeleyEndnote Logotipo do DeGóis 

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.


  © Universidade de Lisboa / SIBUL
Alameda da Universidade | Cidade Universitária | 1649-004 Lisboa | Portugal
Tel. +351 217967624 | Fax +351 217933624 | repositorio@reitoria.ul.pt - Feedback - Statistics
Promotores do RCAAP   Financiadores do RCAAP

Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência PO Sociedade do Conhecimento (POSC) Portal oficial da União Europeia