Utilize este identificador para referenciar este registo: http://hdl.handle.net/10451/21185
Título: OPERATIONALIZATION TO PORTUGAL Beers Criteria of Inappropriate Medication use in the Elderly
Autor: Soares, Maria Augusta
Fernandez-Llimos, Fernando
Lanca, Carmen
Cabrita, Jose
Morais, Jose A.
Palavras-chave: Medicine, General & Internal
Data: 2008
Citação: ACTA MEDICA PORTUGUESA. - Vol. 21, n. 5 (SEP-OCT 2008), p. 441-452
Resumo: Introduction: Elderly drug therapy needs special care considering physiopatological alterations of this age group that increase the risk of adverse drug events occurrence and due to the high number of drugs used. Several tools have been created, as tables of drugs and group of drugs to be avoided in patients of 65 years old and over. Beers Criteria of 2002 update is the most used tool. Goals: To operationalize Beers Criteria to be used by health care professionals in Portugal. Methods: Analysis of the drugs and therapeutic classes included into the Beers Criteria approved for market in Portugal and the identification of other approved substances included in the pharmacological classes mentioned in Beers Criteria. The two tables in the Beers criteria were adapted to substances approved in Portugal, even including other marketed active substances belonging to therapeutic classes mentioned in Beers criteria. Levels of inappropriateness and the potential effects after their use in elderly were also included. In Beers table 1, 34 included substances don't have approval in Portugal, and 4 have different denominations. In Beers table 2, three tricyclic antidepressants, 12 typical antipsychotics, 5 doses for short-action benzodiazepines, and 28 NSAIDs (being two coxibs) were included. Conclusions: The Portuguese operationalization of the Beers Criteria allows the creation of a tool that helps prescribers to choose drugs and doses for a safer prescription to the elderly. These adapted tables allow benchmarking among studies assessing inappropriateness use of drugs in different countries using Beers Criteria.
URI: http://hdl.handle.net/10451/21185
ISSN: 1646-0758
Aparece nas colecções:FF - Produção Científica 2000-2009

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