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Title: Synthesis and Friedlander reactions of 5-amino-4-cyano-1,3-oxazoles
Author: Carreiras, Maria do Carmo
Eleutério, Ana
Dias, Catarina
Brito, Maria Alexandra
Brites, Dora
Marco-Contelles, José
Gómez-Sánchez, Elena
Issue Date: 2007
Publisher: The Japan Institute of Heterocyclic Chemistry
Citation: Heterocycles, Vol. 71, No. 10, 2007, pp. 2249 - 2262
Abstract: The synthesis of 2-substituted 5-amino-4-cyano-1,3-oxazoles (1-4, 6-11) and the Friedländer-type reaction of compounds 1, 3, 4 is described. Compounds 13-17 are tacrine (18) analogues provided by the Friedländer reaction. The anti-cholinesterase activity of compounds 13, 14, 16 and 17 has been investigated.
Peer review: yes
ISSN: 1881-0942
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Appears in Collections:FF - Artigos em Revistas Internacionais

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