Utilize este identificador para referenciar este registo: http://hdl.handle.net/10451/3935
Título: An easy and stereoselective rearrangement of an abietane diterpenoid into a bioactive microstegiol derivative
Autor: Simões, Maria de Fátima
Rijo, Patrícia
Duarte, Aida
Matias, Diogo
Rodríguez, Benjamín
Palavras-chave: Plectranthus ecklonii
Labiatae
Abietanes
Rearranged abietanes
Microstegiol derivative
Acid-washed molecular sieves as catalyst
Data: 2010
Citação: Phytochemistry Letters. December 2010, 3(4) 234-237
Resumo: Parvifloron D was isolated from Plectranthus ecklonii together with sugiol and mixtures of β-sitosterol and stigmasterol and ursolic and oleanolic acids. Treatment of parvifloron D [2α-(4-hydroxy)benzoyloxy-11-hydroxy-5,7,9(11),13-abietatetraen-12-one] with acid-washed molecular sieves gave the microstegiol derivative 2β-(4-hydroxy)benzoyloxy-11β-hydroxy-4(5 → 11),20(10 → 5)diabeo-5(10),6,8,13-abietatetraen-12-one in a moderate yield (26%). The new microstegiol derivative inhibited the growth of some Staphylococcus and Enterococcus species with significant MIC values ranging from 3.91 to 7.81 μg/ml.
Peer review: yes
URI: http://dx.doi.org/10.1016/j.phytol.2010.09.001
http://hdl.handle.net/10451/3935
ISSN: 1874-3900
Versão do Editor: http://www.sciencedirect.com/science/article/pii/S1874390010000790
Aparece nas colecções:FF - Artigos em Revistas Internacionais

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