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Title: Two new diterpenoids from Plectranthus species
Authors: Simões, Maria de Fátima
Rijo, Patrícia
Duarte, Aida
Barbosa, Diana
Matias, Diogo
Delgado, Joana
Cirilo, Nádia
Rodríguez, Benjamín
Keywords: Plectranthus saccatus
Plectranthus porcatus
Biological activity
Issue Date: 2010
Citation: Phytochemistry Letters. December 2010, 3(4) 221-225
Abstract: Two new diterpenoids, ent-7α-acetoxy-15-beyeren-18-oic acid and (13S,15S)-6β,7α,12α,19-tetrahydroxy-13β,16-cyclo-8-abietene-11,14-dione, have been isolated from Plectranthus saccatus and Plectranthus porcatus, respectively, and their structures were established by 1D and 2D NMR spectroscopic studies. The new diterpenes showed no activity against Gram-negative bacteria and Candida albicans (yeast strain). Among Gram-positive bacteria, the lower MIC value was 62.50 μg/ml for the abietane derivative against Staphylococcus aureus ATCC 6538.
Peer review: yes
ISSN: 1874-3900
Publisher Version:
Appears in Collections:FF-DQFT - Artigos em Revistas Internacionais

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