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|Title: ||EULAR evidence-based recommendations for cardiovascular risk management in patients with rheumatoid arthritis and other forms of inflammatory arthritis|
|Authors: ||Peters, M. J. L.|
Symmons, D. P. M.
Dijkmans, B. A. C.
Kvien, T. K.
McInnes, I. B.
Gonzalez-Gay, M. A.
Smulders, Y. M.
Nurmohamed, M. T.
|Keywords: ||Artrite reumatóide|
|Issue Date: ||2010|
|Publisher: ||BMJ Publishing Group|
|Citation: ||Ann Rheum Dis 2010;69:325–331|
|Abstract: ||Objectives: To develop evidence-based EULAR recommendations
for cardiovascular (CV) risk management in
patients with rheumatoid arthritis (RA), ankylosing
spondylitis (AS) and psoriatic arthritis (PsA).
Methods: A multidisciplinary expert committee was
convened as a task force of the EULAR Standing
Committee for Clinical Affairs (ESCCA), comprising 18
members including rheumatologists, cardiologists, internists
and epidemiologists, representing nine European
countries. Problem areas and related keywords for
systematic literature research were identified. A systematic
literature research was performed using MedLine,
Embase and the Cochrane library through to May 2008.
Based on this literature review and in accordance with the
EULAR’s ‘‘standardised operating procedures’’, the multidisciplinary
steering committee formulated evidencebased
and expert opinion-based recommendations for CV
risk screening and management in patients with
Results: Annual CV risk assessment using national
guidelines is recommended for all patients with RA and
should be considered for all patients with AS and PsA.
Any CV risk factors identified should be managed
according to local guidelines. If no local guidelines are
available, CV risk management should be carried out
according to the SCORE function. In addition to
appropriate CV risk management, aggressive suppression
of the inflammatory process is recommended to further
lower the CV risk.
Conclusions: Ten recommendations were made for CV
risk management in patients with RA, AS and PsA. The
strength of the recommendations differed between RA on
the one hand, and AS and PsA, on the other, as evidence
for an increased CV risk is most compelling for RA.|
|Description: ||Additional tables are
published online only at http://
|Peer Reviewed: ||yes|
|Appears in Collections:||FM-IMP-Artigos em Revistas Internacionais|
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