Universidade de Lisboa Repositório da Universidade de Lisboa

Repositório da Universidade de Lisboa >
Faculdade de Medicina (FM) >
Instituto de Medicina Preventiva (FM-IMP) >
FM-IMP-Artigos em Revistas Internacionais >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10451/4859

Título: Difference in atherosclerosis burden in different nations and continents assessed by coronary artery calcium
Autor: Santos, Raul D.
Nasir, Khurram
Rumberger, John A.
Budoff, Matthew J.
Braunstein, Joel B.
Meneghelo, Romeu
Barreiros, Miguel
Pereirinha, Armando
Carvalho, José A. M.
Blumenthal, Roger S.
Raggi, Paolo
Palavras-chave: Coronary artery calcium
Atherosclerosis
Ethnicity
Risk factors
Coronary artery disease
Electron beam computed tomography
Issue Date: 2006
Editora: European Atherosclerosis Society
Citação: Atherosclerosis 187 (2006):378–384
Resumo: We utilized coronary artery calcium scores(CACS) to assess differences in atherosclerosis burden between asymptomatic White populations living in continents with different cardiovascular disease rates. The similarities in the genetic pool between Brazilian and Portuguese Caucasian subjects offered an opportunity to assess the influence of environmnetal factors on the development of atherosclerosis. We reviewed CACS data from 17,563 individuals (12,378 men and 5169 women) collected in the USA (74% of the subjects), Brazil (15% of the subjects) and Portugal (11% of the subjects). CACS was absent in 80 and 88% of Portuguese men and women, compared with 46 and 62% and 33 and 59% of Brazilian and US counterparts (p < 0.0001). Although the US subjects showed the lowest prevalence of risk factors they had a higher median (interquartile range) CACS than the Brazilian and the Portuguese cohorts: 4 (0;87), 1 (0;68) and 0 (0;0), respectively (p < 0.0001). After adjusting for differences in age and cardiovascular risk factors, US men showed higher relative risk ratios of having any CACS than either Brazilian or Portuguese men. Brazilian and US women did not differ as far as risk of CACS although they demonstrated a greater risk than Portuguese women. In this study, significant differences in CACS were detected among three nations in different continents. The CACS differences paralleled the respective cardiovascular mortality rates.
Arbitragem científica: yes
URI: http://hdl.handle.net/10451/4859
http://dx.doi.org/10.1016/j.atherosclerosis.2005.09.017
ISSN: 0021-9150
Versão do Editor: Pode ter acesso à versão integral deste artigo através do portal www.b-on.pt. Isto no caso de efectuar a pesquisa a partir de um IP de um Campus Universitário ou ligado a este através de uma ligação remota tipo VPN ou outra, utilizando este link: http://www.sciencedirect.com/science/article/pii/S0021915005006076
Appears in Collections:FM-IMP-Artigos em Revistas Internacionais

Files in This Item:

File Description SizeFormat
Coronary_artery_calcium.pdfArtigo236,56 kBAdobe PDFView/Open
Restrict Access. You can request a copy!
Statistics
FacebookTwitterDeliciousLinkedInDiggGoogle BookmarksMySpaceOrkut
Formato BibTex mendeley Endnote Logotipo do DeGóis 

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

 

  © Universidade de Lisboa / SIBUL
Alameda da Universidade | Cidade Universitária | 1649-004 Lisboa | Portugal
Tel. +351 217967624 | Fax +351 217933624 | repositorio@reitoria.ul.pt - Feedback - Statistics
DeGóis
  Estamos no RCAAP Governo Português separator Ministério da Educação e Ciência   Fundação para a Ciência e a Tecnologia

Financiado por:

POS_C UE