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|Title:||Implementation of a Functional Semantic Similarity Measure between Gene-Products|
|Authors:||Couto, Francisco M.|
Silva, Mário J.
Coutinho, Pedro M.
|Publisher:||Department of Informatics, University of Lisbon|
|Abstract:||Sequence similarity is a common technique to compare gene-products. However, many applications need to compare gene-products based on what they do, not how they are. Most gene-products are being annotated with terms describing their biological function. These terms are defined in biological ontologies. This makes it possible to implement similarity measures between gene-products based on their behavior. We define FuSSiMeG, a functional similarity measure between gene-products that compares the semantic similarity between the terms in their annotations. Software available from http://xldb.fc.ul.pt/rebil/ssm/|
|Appears in Collections:||FC-DI - Technical Reports|
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